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author:

Huang, Y. (Huang, Y..) [1] | You, C. (You, C..) [2] | Hong, B. (Hong, B..) [3] | Han, X. (Han, X..) [4] | Weng, Z. (Weng, Z..) [5]

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Abstract:

A domino one–pot synthesis of 2-(trifluoromethyl) benzothiazole via copper–mediated three–component cascade reaction starting from the easily accessible starting materials such as o-iodoanilines, methyl trifluoropyruvate, and elemental sulfur is reported. The present strategy displayed a comprehensive substrate scope and good functional group tolerance and enabled access to a variety of substituted 2-(trifluoromethyl) benzothiazoles. A 2-(trifluoromethyl) benzoselenazole has also been synthesized utilizing this reaction methodology. © 2024 Wiley-VCH GmbH.

Keyword:

2-(trifluoromethyl)benzothiazoles copper cyclization fluorine three–component cascade reaction

Community:

  • [ 1 ] [Huang Y.]Fujian Provincial University Engineering Research Center of Green Materials and Chemical Engineering, and Fujian Engineering Research Center of New Chinese lacquer Material, College of Materials and Chemical Engineering, Minjiang University, Fuzhou, 350108, China
  • [ 2 ] [You C.]Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
  • [ 3 ] [Hong B.]Fujian Provincial University Engineering Research Center of Green Materials and Chemical Engineering, and Fujian Engineering Research Center of New Chinese lacquer Material, College of Materials and Chemical Engineering, Minjiang University, Fuzhou, 350108, China
  • [ 4 ] [Han X.]Testing and Analysis Center, Soochow University, Suzhou, 215123, China
  • [ 5 ] [Weng Z.]Fujian Provincial University Engineering Research Center of Green Materials and Chemical Engineering, and Fujian Engineering Research Center of New Chinese lacquer Material, College of Materials and Chemical Engineering, Minjiang University, Fuzhou, 350108, China
  • [ 6 ] [Weng Z.]Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou, 350108, China

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Source :

Chemistry - An Asian Journal

ISSN: 1861-4728

Year: 2024

Issue: 13

Volume: 19

3 . 5 0 0

JCR@2023

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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