A　drop-weight　impact　testing　machine　was　used　to　conduct　an　impact　test　on　15　specimens　in　order　to　examine　the　impact　resistance　of　high-strength　(HS)　steel　beams　with　hexagonal　web　openings　(SBHWO).　The　test　findings　demonstrate　that　as　steel　strength　increases,　maximal　impact　force　and　impact　platform　value　rise,　while　maximum　displacement,　residual　displacement,　beam-end　rotation,　reduction　ratio　of　opening　area,　and　energy　absorption　ratio　decrease.　The　use　of　high-strength　steel　can　significantly　improve　the　impact　resistance　of　the　SBHWO.　When　steel　Q235　was　lifted　to　steel　Q550,　the　average　increase　of　impact　peak　and　impact　platform　value　was　17.94%　and　90.80%,　respectively,　and　the　average　reduction　range　of　maximum　displacement　and　residual　displacement　in　the　span　was　45.36%　and　55.30%,　respectively.　After　steel　Q550　was　upgraded　to　steel　Q690,　the　improvement　effect　of　impact　resistance　is　small.　Empirical　equations　of　the　relationship　between　impact　energy,steel　strength　and　dynamic　responses　were　established.