Quantum　dot　light-emitting　diodes　(QLEDs),　owing　to　their　exceptional　performances　in　device　efficiency,　color　purity/tunability　in　the　visible　region　and　solution-processing　ability　on　various　substrates,　become　a　potential　candidate　for　flexible　and　ultrathin　electroluminescent　(EL)　lighting　and　display.　Moreover,　beyond　the　lighting　and　display,　flexible　QLEDs　are　enabled　with　endless　possibilities　in　the　era　of　the　internet　of　things　and　artificial　intelligence　by　acting　as　input/output　ports　in　wearable　integrated　systems.　Challenges　remain　in　the　development　of　flexible　QLEDs　with　the　goals　for　high　performance,　excellent　flexibility/even　stretchability,　and　emerging　applications.　In　this　paper,　the　recent　developments　of　QLEDs　including　quantum　dot　materials,　working　mechanism,　flexible/stretchable　strategies　and　patterning　strategies,　and　highlight　its　emerging　multifunctional　integrations　and　smart　applications　covering　wearable　optical　medical　devices,　pressure-sensing　EL　devices,　and　neural　smart　EL　devices,　are　reviewed.　The　remaining　challenges　are　also　summarized　and　an　outlook　on　the　future　development　of　flexible　QLEDs　made.　The　review　is　expected　to　offer　a　systematic　understanding　and　valuable　inspiration　for　flexible　QLEDs　to　simultaneously　satisfy　optoelectronic　and　flexible　properties　for　emerging　applications.　©　2023　Wiley-VCH　GmbH.