The　TiO2　film　was　coated　on　poly　vinyl　chloride　(PVC)　surface　by　dip-coating　process　from　TiO2-PVC-THF　suspension.　The　morphology　and　crystal　structure　of　the　as-synthesized　samples　were　characterized　by　SEM　and　XRD.　The　photocatalytic　properties　were　measured　by　the　photodegradation　reaction　of　RhB　and　the　anti-adhesion　and　anti-bacteria　for　Escherichia　coli.　The　results　show　that　the　resultant　TiO2　film　is　well-conglutinated　on　PVC　surface　and　has　the　same　crystal　structure　as　the　original　TiO2　powder.　The　TiO2/PVC　shows　excellent　photocatalytic　activity　for　the　degradation　of　aqueous　RhB　and　the　activity　increases　with　increasing　reaction　time　and　tends　toward　stable　after　accumulative　illumination　for　11.5　IN.　The　TiO2　film　shows　good　bacterial　anti-adhesion　activity　following　photo-activation　and　sterilization　property　under　UV　irradiation.　The　E.　coli　can　be　killed　completely　after　UV　irradiation　for　1.5　h.　(C)　2008　Wiley　Periodicals,　Inc.　J　Biomed　Mater　Res　Part　13:　Appl　Biomater　87B:　425-431,　2008