Two　new　bichromophoric　ruthenium(II)　complexes,　[Ru(bpy)2(bpy-CM)](PF6)2　and　[Ru(bpy)2(bpy-CM343)](PF6)2　(bpy=2,2＇-bipyridine,　CM=coumarin)　with　appended　coumarin　ligands　have　been　designed　and　synthesized.　The　energy-transfer-based　sensing　of　esterase　by　the　complexes　has　been　studied　by　using　UV/Vis　and　luminescence　spectroscopic　methods.　The　cytotoxicity　and　the　cellular　uptake　of　one　of　the　complexes　have　also　been　investigated.