Indexed by:
Abstract:
An effective protocol for the difluoromethylation of tosylhydrazone compounds under mild conditions is disclosed via a transition-metal-free pathway; ClCF2H is almost quantitatively converted under the set conditions. In this transformation, the process in which tosylhydrazones are decomposed to lead to diazo species has been completely suppressed. This transformation enables tosylhydrazones as efficient difluorocarbene scavengers and the corresponding difluoromethylated products were obtained in good yields with high functional-group tolerance.
Keyword:
Reprint 's Address:
Email:
Version:
Source :
ASIAN JOURNAL OF ORGANIC CHEMISTRY
ISSN: 2193-5807
Year: 2019
Issue: 5
Volume: 8
Page: 694-697
3 . 1 3
JCR@2019
2 . 8 0 0
JCR@2023
ESI Discipline: CHEMISTRY;
ESI HC Threshold:184
JCR Journal Grade:2
CAS Journal Grade:3
Cited Count:
WoS CC Cited Count: 16
SCOPUS Cited Count: 17
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 2
Affiliated Colleges: