Herein,　we　report　a　nickel-catalyzed　crossing-coupling　reaction　for　the　synthesis　of　diaryl　ethers.　The　desired　products　are　achieved　by　coupling　heterocyclic　alcohols　with　aryl　bromides　bearing　strong　electron　withdrawing　nitro　group　under　the　catalyst　system　of　NiCl2(PPh3)(2)　and　weak　base　KHCO3.　This　mild　reaction　exhibits　a　broad　functional　group　tolerance.　Compound　4　as　an　important　intermediate　is　suitable　for　further　structural　modification　of　MALT1　inhibitor　MI-2.