Microbial　infection　in　open　wounds　can　delay　healing　and　lead　to　severe　complications.　This　study　introduces　a　bacterial-responsive　cellulose-based　fabric　wound　dressing　(Fabric-PAC)　with　integrated　antimicrobial　and　hemostatic　functions.　Fabric-PAC　is　chemically　modified　with　polyphosphate　(PolyP)　and　low-dose　silver　nanoparticles　(AgNPs),　and　further　functionalized　with　a　phthalocyanine-based　photosensitizer　via　supramolecular　interactions　on　surface.　Upon　contact　with　bacteria,　the　photosensitizer　is　displaced,　exposing　PolyP　to　initiate　blood　coagulation　and　platelet-deriven　tissue　remodeling,　promoting　wound　healing.　Simultaneously,　AgNPs　are　also　exposed　to　provede　sustained　bacteriostasis.　Moreover,　the　positively　charged　photosensitizer　tightly　attaches　on　the　bacterial　surface,　and　triggers　the　antimicrobial　photodynamic　effect　upon　illumination,　rapidly　eliminating　pathogens.　This　study　not　only　introduces　a　bacteria-responsive　wound　dressing　with　synergistic　antimicrobial　and　hemostatic　effects,　but　also　offers　a　new　strategy　for　the　functionalization　of　cellulose-based　materials.