The　large-scale　fabrication　and　patterning　of　artificial　perceptual　systems　are　vital　for　the　development　of　bionic　systems.　Traditional　patterning　processes　are　often　constrained　by　the　use　of　mask　versions,　which　are　not　only　expensive　but　also　challenging　to　produce　on　a　large　scale.　Inkjet　printing　technology　with　maskless　patterning　capability　is　well　suited　for　current　demands　for　large-scale　preparation　and　patterning.　However,　the　application　of　printing　techniques　is　typically　confined　to　the　production　of　simple　devices　or　the　preparation　of　patterned　active　layers　within　more　complex　devices.　In　this　study,　we　successfully　fabricated　fully　inkjet-printed　indium　gallium　zinc　oxide　(IGZO)　memristor　arrays　to　mimic　artificial　nociceptor　(pain　receptors).　By　integrating　a　layer　of　silver　into　the　all　metal-oxide　indium　tin　oxide　(ITO)/IGZO/ITO　memristor,　we　achieved　stable　threshold　switching　characteristics,　a　large　current　switching　ratio　of　105,　excellent　switching　durability　of　104　cycles　scans,　and　excellent　spatial　uniformity.　We　investigated　the　Ag-based　conductive　filament　conduction　mode　and　mimic　LIF　characteristics　(leaky,　integrate　and　fire),　demonstrating　the　potential　of　the　memristor　as　an　artificial　neuron.　Lastly,　we　successfully　implemented　artificial　nociceptor,　including　“threshold　fire”,　“relaxation”,　“non-adaptation”,　and　“sensitization”,　leveraging　the　stable　threshold　switching　properties　of　the　device.　Our　work　demonstrates　the　significant　potential　of　inkjet　printing　technology　in　the　realization　of　bionic　systems.　(Figure　presented.)　©　Science　China　Press　2024.