Plasmonic　gold　nanocrystal　represents　plasmonic　metal　nanomaterials,　and　has　a　variety　of　unique　and　beneficial　properties,　such　as　optical　signal　enhancement,　catalytic　activity,　and　photothermal　properties　tuned　by　local　temperature,　which　are　useful　in　physical,　chemical,　and　biological　applications.　In　addition,　the　inherent　properties　of　predictable　programmability,　sequence　specificity,　and　structural　plasticity　provide　DNA　nanostructures　with　precise　controllability,　spatial　addressability,　and　targeting　recognition,　serving　as　ideal　ligands　to　link　or　position　building　blocks　during　the　self-assembly　process.　Self-assembly　is　a　common　technique　for　the　organization　of　prefabricated　and　discrete　nanoparticle　blocks　for　the　construction　of　extremely　sophisticated　nanocomposites.　To　this　end,　the　integration　of　DNA　nanotechnology　with　Au　nanomaterials,　followed　by　assembly　of　DNA-functionalized　Au　nanomaterials　can　form　novel　functional　Au　nanomaterials　that　are　difficult　to　obtain　through　conventional　methods.　Here,　recent　progress　in　DNA-assembled　Au　nanostructures　of　various　shapes　is　summarized,　and　their　functions　are　discussed.　The　fabrication　strategies　that　employ　DNA　for　the　self-assembly　of　Au　nanostructures,　including　dimers,　tetramers,　satellites,　nanochains,　and　other　nanostructures　with　more　complex　geometric　configurations　are　first　described.　Then,　the　characteristic　optical　properties　and　applications　of　biosensing,　bioimaging,　drug　delivery,　and　therapy　are　discussed.　Finally,　the　remaining　challenges　and　prospects　are　elucidated.