Query：
学者姓名：宋继彬
Refining：
Year
Type
Indexed by
Source
Complex
Former Name
Co-
Language
Clean All
Abstract ：
Chemiluminescence (CL) is a self-illuminating phenomenon fueled by chemical energy instead of extra excited light, which features superiority in sensitivity, signal-to-background ratios, and imaging depth. Strategies to synthesize a CL emission unimolecular skeleton in the second near-infrared window (NIR-II) and a unimolecular probe with direct duplex NIR-II [CL/fluorescence (FL)] emission are lacking. Here, we employ modular synthesis routes to construct a series of directly activated NIR-II CL emission unimolecular probes with a maximum emission wavelength of up to 1060 nm, and use them for real-time and continuous detection of the superoxide anion generated in acetaminophen induced liver injury in a female mice model under both NIR-II CL and NIR-II FL imaging channels. Thus, this study establishes a directly activatable NIR-II CL emission unimolecular skeleton, validating the scalability of this duplex NIR-II CL/FL imaging platform in bioactive molecule detection and disease diagnosis.
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Chen, Zhongxiang , Li, Qian , Wu, Ying et al. Molecular Engineering of Direct Activated NIR-II Chemiluminescence Platform for In Vivo Chemiluminescence-fluorescence Duplex Imaging [J]. | NATURE COMMUNICATIONS , 2025 , 16 (1) . |
| MLA | Chen, Zhongxiang et al. "Molecular Engineering of Direct Activated NIR-II Chemiluminescence Platform for In Vivo Chemiluminescence-fluorescence Duplex Imaging" . | NATURE COMMUNICATIONS 16 . 1 (2025) . |
| APA | Chen, Zhongxiang , Li, Qian , Wu, Ying , Liu, Jianyong , Liu, Luntao , Su, Lichao et al. Molecular Engineering of Direct Activated NIR-II Chemiluminescence Platform for In Vivo Chemiluminescence-fluorescence Duplex Imaging . | NATURE COMMUNICATIONS , 2025 , 16 (1) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Stimuli-triggered release and alleviating resistance of iridium(Ⅲ)-based drugs at tumor sites re-mains challengeable for clinical hepatoma therapy.Herein,a doxorubicin@iridium-transferrin(DOX@Ir-TF)nanovesicle was synthesized by carboxylated-transferrin(TF)and doxorubicin-loaded amphiphilic iridium-amino with quaternary ammonium(QA)groups and disulfide bonds.The QA groups enhanced photophysical properties and broadened production capacity of photoinduced-reactive oxygen species(ROS),while the disulfide-bridged bonds regulated oxidative stress levels through reacting with glu-tathione(GSH);simultaneously,modification of TF improved recognition and endocytosis of the nanovesi-cle for tumor cells.Based on in-vitro results,a controlled-release behavior of DOX upon a dual-responsiveness of GSH and near-infrared ray(NIR)irradiation was presented,along with high-efficiency generation of ROS.After an intravenous injection,the nanovesicle was targeted at tumor sites,realizing TF-navigated photoacoustic imaging guidance and synergistic chemotherapy-photodynamic therapy under NIR/GSH stimulations.Overall,newly-synthesized DOX@Ir-TF nanovesicle provided a potential in subcuta-neous hepatocellular carcinoma therapy due to integrations of targeting delivery,dual-stimuli responsive release,synergistic therapy strategy,and real-time monitoring.
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Jinyu Guo , Yandai Lin , Shaohua He et al. Utilizing dual-responsive iridium(Ⅲ)complex for hepatocellular carcinoma:Integrating photoacoustic imaging with chemotherapy and photodynamic therapy [J]. | 中国化学快报（英文版） , 2024 , 35 (9) : 296-302 . |
| MLA | Jinyu Guo et al. "Utilizing dual-responsive iridium(Ⅲ)complex for hepatocellular carcinoma:Integrating photoacoustic imaging with chemotherapy and photodynamic therapy" . | 中国化学快报（英文版） 35 . 9 (2024) : 296-302 . |
| APA | Jinyu Guo , Yandai Lin , Shaohua He , Yueqing Chen , Fenglu Li , Renjie Ruan et al. Utilizing dual-responsive iridium(Ⅲ)complex for hepatocellular carcinoma:Integrating photoacoustic imaging with chemotherapy and photodynamic therapy . | 中国化学快报（英文版） , 2024 , 35 (9) , 296-302 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Large osseous void, postsurgical neoplastic recurrence, and slow bone-cartilage repair rate raise an imperative need to develop functional scaffold in clinical osteosarcoma treatment. Herein, a bionic bilayer scaffold constituting croconaine dye-polyethylene glycol@sodium alginate hydrogel and poly(L-lactide)/hydroxyapatite polymer matrix is fabricated to simultaneously achieve a highly efficient killing of osteosarcoma and an accelerated osteochondral regeneration. First, biomimetic osteochondral structure along with adequate interfacial interaction of the bilayer scaffold provide a structural reinforcement for transverse osseointegration and osteochondral regeneration, as evidenced by upregulated specific expressions of collagen type-I, osteopontin, and runt-related transcription factor 2. Meanwhile, thermal ablation of the synthesized nanoparticles and mitochondrial dysfunction caused by continuously released hydroxyapatite induce residual tumor necrosis synergistically. To validate the capabilities of inhibiting tumor growth and promoting osteochondral regeneration of our proposed scaffold, a novel orthotopic osteosarcoma model simulating clinical treatment scenarios of bone tumors is established on rats. Based on amounts of in vitro and in vivo results, an effective killing of osteosarcoma and a suitable osteal-microenvironment modulation of such bionic bilayer composite scaffold are achieved, which provides insightful implications for photonic hyperthermia therapy against osteosarcoma and following osseous tissue regeneration.
Keyword ：
bilayer scaffold bilayer scaffold biomaterials biomaterials orthotopicosteosarcoma orthotopicosteosarcoma osteochondral regeneration osteochondral regeneration photonic hyperthermiatherapy photonic hyperthermiatherapy
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Gong, Chenchi , Wang, Jun , Tang, Faqiang et al. Bionic Bilayer Scaffold for Synchronous Hyperthermia Therapy of Orthotopic Osteosarcoma and Osteochondral Regeneration [J]. | ACS APPLIED MATERIALS & INTERFACES , 2024 , 16 (7) : 8538-8553 . |
| MLA | Gong, Chenchi et al. "Bionic Bilayer Scaffold for Synchronous Hyperthermia Therapy of Orthotopic Osteosarcoma and Osteochondral Regeneration" . | ACS APPLIED MATERIALS & INTERFACES 16 . 7 (2024) : 8538-8553 . |
| APA | Gong, Chenchi , Wang, Jun , Tang, Faqiang , Tong, Dongmei , Wang, Ziyi , Zhou, Zijie et al. Bionic Bilayer Scaffold for Synchronous Hyperthermia Therapy of Orthotopic Osteosarcoma and Osteochondral Regeneration . | ACS APPLIED MATERIALS & INTERFACES , 2024 , 16 (7) , 8538-8553 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
The external quantum efficiency (EQE) enhancement of different sized GaN micro-light-emitting diodes (mu LEDs) by using localized surface plasmons (LSPs) have been studied. Silver nanoparticles (Ag NPs) are attached to the sidewalls of mu LEDs by spin-coating so as to be effectively coupled with the multiple quantum well (MQW) of mu LEDs and generate the LSPs. In the mu LEDs with 20 x 20 mu m2 large mesas, the LSPs can effectively inhibit the efficiency droop. Compared to the mu LED samples without the LSPs coupling, the EQE has been enhanced by about 8% at a high current density of 20,000 A/cm2. This work confirms the effectiveness of the LSPs technology in improving the mu LED performances, which is originally practiced only on the basal faces of conventional LEDs.
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Du, Zaifa , Sun, Jie , Feng, Hongjuan et al. Efficiency enhancement of micro-light-emitting diode with shrinking size by localized surface plasmons coupling [J]. | APPLIED PHYSICS B-LASERS AND OPTICS , 2024 , 130 (3) . |
| MLA | Du, Zaifa et al. "Efficiency enhancement of micro-light-emitting diode with shrinking size by localized surface plasmons coupling" . | APPLIED PHYSICS B-LASERS AND OPTICS 130 . 3 (2024) . |
| APA | Du, Zaifa , Sun, Jie , Feng, Hongjuan , Tang, Penghao , Guo, Weiling , Han, Kai et al. Efficiency enhancement of micro-light-emitting diode with shrinking size by localized surface plasmons coupling . | APPLIED PHYSICS B-LASERS AND OPTICS , 2024 , 130 (3) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Stimuli-triggered release and alleviating resistance of iridium(III)-based drugs at tumor sites remains challengeable for clinical hepatoma therapy. Herein, a doxorubicin@iridium-transferrin (DOX@IrTF) nanovesicle was synthesized by carboxylated-transferrin (TF) and doxorubicin-loaded amphiphilic iridium-amino with quaternary ammonium (QA) groups and disulfide bonds. The QA groups enhanced photophysical properties and broadened production capacity of photoinduced-reactive oxygen species (ROS), while the disulfide-bridged bonds regulated oxidative stress levels through reacting with glutathione (GSH); simultaneously, modification of TF improved recognition and endocytosis of the nanovesicle for tumor cells. Based on in -vitro results, a controlled-release behavior of DOX upon a dualresponsiveness of GSH and near-infrared ray (NIR) irradiation was presented, along with high-efficiency generation of ROS. After an intravenous injection, the nanovesicle was targeted at tumor sites, realizing TF-navigated photoacoustic imaging guidance and synergistic chemotherapy-photodynamic therapy under NIR/GSH stimulations. Overall, newly-synthesized DOX@Ir-TF nanovesicle provided a potential in subcutaneous hepatocellular carcinoma therapy due to integrations of targeting delivery, dual -stimuli responsive release, synergistic therapy strategy, and real -time monitoring. (c) 2024 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
Keyword ：
Amphiphilic iridium complex Amphiphilic iridium complex NIR/GSH dual-responsiveness NIR/GSH dual-responsiveness Photoacoustic imaging Photoacoustic imaging Synergistic tumor therapy Synergistic tumor therapy Transferrin targeting Transferrin targeting
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Guo, Jinyu , Lin, Yandai , He, Shaohua et al. Utilizing dual-responsive iridium(III) complex for hepatocellular carcinoma: Integrating photoacoustic imaging with chemotherapy and photodynamic therapy [J]. | CHINESE CHEMICAL LETTERS , 2024 , 35 (9) . |
| MLA | Guo, Jinyu et al. "Utilizing dual-responsive iridium(III) complex for hepatocellular carcinoma: Integrating photoacoustic imaging with chemotherapy and photodynamic therapy" . | CHINESE CHEMICAL LETTERS 35 . 9 (2024) . |
| APA | Guo, Jinyu , Lin, Yandai , He, Shaohua , Chen, Yueqing , Li, Fenglu , Ruan, Renjie et al. Utilizing dual-responsive iridium(III) complex for hepatocellular carcinoma: Integrating photoacoustic imaging with chemotherapy and photodynamic therapy . | CHINESE CHEMICAL LETTERS , 2024 , 35 (9) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Afterglow fluorescence imaging has been extensively assessed in ultrasensitive bioimaging. Since it eliminates the need for real-time excitation light and thereby circumvents the autofluorescence background of tissue, it holds tremendous potential in accurate biomedical imaging. However, current afterglow probes are rare and emit light only in the visible to near-infrared (NIR) range, which is inadequate for in vivo imaging. To resolve this issue, an ultrasound (US)-activated NIR-II afterglow luminescence probe (NPs-Ce4-SN) emitting afterglow luminescence with a peak at similar to 1100 nm was developed. This peak is nearly 400 nm red-shifted compared with other reported afterglow probes. Of note, after US termination, NPs-Ce4-SN undergoes energy transformation to produce 1O2 and subsequently undergoes internal oxidation-reduction reaction to produce NIR-II afterglow, generating high signal-to-noise ratio and high-penetration depth imaging. In vitro and in vivo NIR-II afterglow imaging experiments revealed that NPs-Ce4-SN has good biocompatibility and deep tissue penetration depth, suggesting a diagnostic strategy for in vivo tumor imaging with a high signal-to-noise ratio.
Keyword ：
afterglow imaging afterglow imaging NIR-II NIR-II probe probe tumor imaging tumor imaging ultrasound-activated ultrasound-activated
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Yuan, Meng , Fang, Xiao , Liu, Wenzheng et al. Ultrasound-Activated Near-Infrared-II Afterglow Luminescence for Precise Cancer Imaging [J]. | ACS APPLIED BIO MATERIALS , 2024 , 8 (1) : 368-373 . |
| MLA | Yuan, Meng et al. "Ultrasound-Activated Near-Infrared-II Afterglow Luminescence for Precise Cancer Imaging" . | ACS APPLIED BIO MATERIALS 8 . 1 (2024) : 368-373 . |
| APA | Yuan, Meng , Fang, Xiao , Liu, Wenzheng , Ge, Xiaoguang , Wu, Ying , Su, Lichao et al. Ultrasound-Activated Near-Infrared-II Afterglow Luminescence for Precise Cancer Imaging . | ACS APPLIED BIO MATERIALS , 2024 , 8 (1) , 368-373 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Surface-enhanced Raman scattering (SERS) is a feasible and ultra-sensitive method for biomedical imaging and disease diagnosis. SERS is widely applied to in vivo imaging due to the development of functional nanoparticles encoded by Raman active molecules (SERS nanoprobes) and improvements in instruments. Herein, the recent developments in SERS active materials and their in vivo imaging and biosensing applications are overviewed. Various SERS substrates that have been successfully used for in vivo imaging are described. Then, the applications of SERS imaging in cancer detection and in vivo intraoperative guidance are summarized. The role of highly sensitive SERS biosensors in guiding the detection and prevention of diseases is discussed in detail. Moreover, its role in the identification and resection of microtumors and as a diagnostic and therapeutic platform is also reviewed. Finally, the progress and challenges associated with SERS active materials, equipment, and clinical translation are described. The present evidence suggests that SERS could be applied in clinical practice in the future.
Keyword ：
biosensing biosensing diagnosis diagnosis Raman mapping Raman mapping self-assembly self-assembly surface-enhanced Raman scattering surface-enhanced Raman scattering
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Li, Qingqing , Huo, Hongqi , Wu, Ying et al. Design and Synthesis of SERS Materials for In Vivo Molecular Imaging and Biosensing [J]. | ADVANCED SCIENCE , 2023 , 10 (8) . |
| MLA | Li, Qingqing et al. "Design and Synthesis of SERS Materials for In Vivo Molecular Imaging and Biosensing" . | ADVANCED SCIENCE 10 . 8 (2023) . |
| APA | Li, Qingqing , Huo, Hongqi , Wu, Ying , Chen, Lanlan , Su, Lichao , Zhang, Xuan et al. Design and Synthesis of SERS Materials for In Vivo Molecular Imaging and Biosensing . | ADVANCED SCIENCE , 2023 , 10 (8) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Manufacturing heteronanostructures with specific physicochemical characteristics and tightly controllable designs is very appealing. Herein, we reported NIR-II light-driven dual plasmonic (AuNR-SiO2-Cu7S4) antimicrobial nanomotors with an intended Janus configuration through the overgrowth of copper rich Cu7S4 nanocrystals at only one high-curvature site of Au nanorods (Au NRs). These nanomotors were applied for photoacoustic imaging (PAI)-guided synergistic photothermal and photocatalytic treatment of bacterial infections. Both the photothermal performance and photocatalytic activity of the nanomotors are dramatically improved owing to the strong plasmon coupling between Au NRs and the Cu7S4 component and enhanced energy transfer. The motion behavior of nanomotors promotes transdermal penetration and enhances the matter-bacteria interaction. More importantly, the directional navigation and synergistic antimicrobial activity of the nanomotors could be synchronously driven by NIR-II light. The marriage of active motion and enhanced antibacterial activity resulted in the expected good antibacterial effects in an abscess infection mouse model.
Keyword ：
bacterial infections bacterial infections gold nanorod gold nanorod Janus nanoparticle Janus nanoparticle nanomotor nanomotor photoacoustic imaging photoacoustic imaging
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Liu, Luntao , Li, Shuqin , Yang, Kaiqiong et al. Drug-Free Antimicrobial Nanomotor for Precise Treatment of Multidrug-Resistant Bacterial Infections [J]. | NANO LETTERS , 2023 , 23 (9) : 3929-3938 . |
| MLA | Liu, Luntao et al. "Drug-Free Antimicrobial Nanomotor for Precise Treatment of Multidrug-Resistant Bacterial Infections" . | NANO LETTERS 23 . 9 (2023) : 3929-3938 . |
| APA | Liu, Luntao , Li, Shuqin , Yang, Kaiqiong , Chen, Zhongxiang , Li, Qingqing , Zheng, Liting et al. Drug-Free Antimicrobial Nanomotor for Precise Treatment of Multidrug-Resistant Bacterial Infections . | NANO LETTERS , 2023 , 23 (9) , 3929-3938 . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Background Photothermal therapy (PTT) in the second near-infrared (NIR-II) window has attracted extensive attention due to the benefits in high maximum permissible exposure and penetration depth. Current photothermal agents generally show a broadband absorption accompanied by a gradual attenuation of absorption in the NIR-II window, leading to poor effect of PTT. It remains a great challenge to gain photothermal agents with strong and characteristic absorption in NIR-II regions. To overcome this problem, based on carbon dots (CDs)-mediated growth strategy, we proposed a simple and feasible approach to prepare plasmonic gold nanodendrites (AuNDs) with NIR-II absorption to enhance the therapeutic effect of PTT.Results By rationally regulating the size and branch length of AuNDs, the AuNDs exhibited a broadband absorption from 300 to 1350 nm, with two characteristic absorption peaks located at 1077 and 1265 nm. The AuNDs demonstrated desired optical photothermal conversion efficiency (38.0%), which was further applied in NIR-II photoacoustic imaging (PAI) and PTT in human colon cancer cells (HCT 116)-tumor-bearing mice model. The tumor cells could be effectively eliminated in vivo under 1064 nm laser irradiation by the guidance of PAI.Conclusions We reported a simple but powerful synthetic method to obtain the unique AuNDs with strong and characteristic absorption peaks in the NIR-II window. This study provides a promising solution to tuning the growth of nanoparticles for bioimaging and phototherapy in the NIR-II window.
Keyword ：
Carbon dots Carbon dots Gold nanodendrites Gold nanodendrites Photoacoustic imaging Photoacoustic imaging Photothermal therapy Photothermal therapy Second near-infrared window Second near-infrared window
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Liu, Guoyong , Wang, Shuxian , Wang, Shumin et al. Carbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy [J]. | JOURNAL OF NANOBIOTECHNOLOGY , 2023 , 21 (1) . |
| MLA | Liu, Guoyong et al. "Carbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy" . | JOURNAL OF NANOBIOTECHNOLOGY 21 . 1 (2023) . |
| APA | Liu, Guoyong , Wang, Shuxian , Wang, Shumin , Wu, Rongrong , Li, Hui , Zha, Menglei et al. Carbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy . | JOURNAL OF NANOBIOTECHNOLOGY , 2023 , 21 (1) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Abstract ：
Radiotherapy (RT) is an effective and widely applied cancer treatment strategy in clinic. However, it usually suffers from radioresistance of tumor cells and severs side effects of excessive radiation dose. Therefore, it is highly significant to improve radiotherapeutic performance and monitor real-time tumor response, achieving precise and safe RT. Herein, an X-ray responsive radio-pharmaceutical molecule containing chemical radiosensitizers of diselenide and nitroimidazole (BBT-IR/Se-MN) is reported. BBT-IR/Se-MN exhibits enhanced radiotherapeutic effect via a multifaceted mechanisms and self-monitoring ROS levels in tumors during RT. Under X-ray irradiation, the diselenide produces high levels of ROS, leading to enhanced DNA damage of cancer cell. Afterwards, the nitroimidazole in the molecule inhibits the damaged DNA repair, offering a synergetic radiosensitization effect of cancer. Moreover, the probe shows low and high NIR-II fluorescence ratios in the absence and presence of ROS, which is suitable for precise and quantitative monitoring of ROS during sensitized RT. The integrated system is successfully applied for radiosensitization and the early prediction of in vitro and in vivo RT efficacy.
Keyword ：
Activatable Probe Activatable Probe Biosensor Biosensor NIR-II Fluorescence Imaging NIR-II Fluorescence Imaging Radiotherapy Radiotherapy X-Ray X-Ray
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Ge, Xiaoguang , Su, Lichao , Chen, Zhongxiang et al. A Radio-Pharmaceutical Fluorescent Probe for Synergistic Cancer Radiotherapy and Ratiometric Imaging of Tumor Reactive Oxygen Species [J]. | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , 2023 , 62 (29) . |
| MLA | Ge, Xiaoguang et al. "A Radio-Pharmaceutical Fluorescent Probe for Synergistic Cancer Radiotherapy and Ratiometric Imaging of Tumor Reactive Oxygen Species" . | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 62 . 29 (2023) . |
| APA | Ge, Xiaoguang , Su, Lichao , Chen, Zhongxiang , Zhu, Kang , Zhang, Xuan , Wu, Ying et al. A Radio-Pharmaceutical Fluorescent Probe for Synergistic Cancer Radiotherapy and Ratiometric Imaging of Tumor Reactive Oxygen Species . | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , 2023 , 62 (29) . |
| Export to | NoteExpress RIS BibTex |
Version ：
Export
| Results： |
Selected to |
| Format： |
