The　salicylic　acid　imprinted　polymer　microspheres　(SMIP)　were　synthesized　by　emulsion　polymerization　using　salicylic　acid　as　template　and　ethylene　glycol　dimethacrylate　as　crosslinker.　The　interaction　between　the　template　and　functional　monomers　was　analyzed　by　UV　subtractive　spectroscopy.　The　effects　of　different　kinds　of　functional　monomers,　molar　ratio　of　template　to　functional　monomer,　dosage　of　crosslinker　and　elution　solvent　on　the　adsorption　ability　of　SMIP　were　investigated　by　fluorescence　spectrophotometry.　The　morphology　and　size　distribution　of　SMIP　were　detected　by　SEM　and　Nanophox　particle　size　analyzer.　The　results　showed　that　the　SMIP　prepared　by　using　acrylamide　as　functional　monomer　possessed　higher　adsorption　ability　than　the　blank　polymer　with　the　same　chemical　composition,　and　the　imprinting　factor　reached　1.61.　The　particle　size　of　SMIP　was　about　60　nm　and　the　size　distribution　was　narrow.