In　this　paper,　we　study　the　cooperative　global　output　regulation　problem　for　a　class　of　heterogeneous　second　order　nonlinear　uncertain　multi-agent　systems.　We　first　introduce　a　type　of　distributed　internal　model　that　converts　the　cooperative　global　output　regulation　problem　into　the　global　robust　stabilization　problem　of　the　so-called　augmented　multi-agent　system.　Then　we　further　globally　stabilize　this　augmented　multi-agent　system　via　a　distributed　state　feedback　control　law,　thus　leading　to　the　solution　of　the　original　problem.　A　special　case　of　our　result　leads　to　the　solution　of　the　global　leader-following　consensus　problem　for　the　second　order　nonlinear　multi-agent　systems　without　satisfying　the　global　Lipschitz　condition.©　2013　Elsevier　Ltd.　All　rights　reserved.