Mo-Cu　ore　from　Bangpu　was　crushed　by　high　pressure　grinding　rolls(HPGR)　and　jaw　crusher(JC),　and　grinding-flotation　test　of　the　product　crushed　by　different　crushing　processes　was　carried　out.　Crushing　characteristics　of　HPGR　of　ore　was　studied　by　scanning　electron　microscopy(SEM),　dissociation　character　of　grinding　product　was　studied　by　mineral　liberation　analyzer(MLA),　and　the　best　grinding　fineness　and　flotation　process　conditions　were　studied　from　the　reagent　dosage　and　other　aspects.　The　results　show　that　the　best　grinding　fineness　of　the　product　with　size　less　than　0.074　mm　crushed　by　HPGR　and　JC　are　65%　and　75%,　respectively.　The　floatation　effect　of　the　grinding　product　crushed　by　HPGR　are　better　than　that　crushed　by　JC,　and　the　molybdenum　grade,　molybdenum　recovery　of　molybdenum　rougher　concentrate,　copper　grade,　copper　recovery　of　copper　rougher　concentrate　of　HPGR　products　when　the　grinding　fineness　less　than　0.074　mm　content　is　65%　comparing　with　JC　products　when　the　grinding　fineness　less　than　0.074　mm　content　is　75%,　respectively,　high　0.83%,　high　1.03%,　low　0.02%,　high　2.66%.　The　phenomenon　of　selective　combinations　occurs　when　crushed　by　HPGR,　and　the　phenomenon　of　selective　dissociation　occurs　when　the　product　crushed　by　HPGR　is　grinding.　The　＇HPGR　selective　crushing-selective　dissociation　of　the　product　was　grinding　by　ball　milling-flotation＇　technical　scheme　was　put　forward.　©　2016,　Science　Press.　All　right　reserved.