Molybdenum-Copper　ore　from　Bangpu,　Mozhugongka　County,　Tibet　was　crushed　by　high　pressure　grinding　rolls　(HPGR)　and　jaw　crusher　and　the　Bond　work　indexes　of　ball　mill　by　different　crushing　manners　at　different　target　particle　sizes　were　measured,　and　the　influence　of　grinding　fineness　on　the　work　indexes　of　ball　mill　by　different　crushing　manners　was　studied,　and　the　graphical　user　interface　of　Bond　work　index　of　ball　mill　of　Bangpu　Mo-Cu　Ore　by　high　pressure　grinding　rolls　was　established.　The　results　show　that,　the　work　indexes　of　ball　mill　by　HPGR　are　lower　than　that　by　Jaw　Crusher.　It　can　be　forecast　that　energy　saving　of　the　crushed　product　by　HPGR　is　more　obvious　than　that　by　Jaw　Crusher　when　the　grinding　fineness　(mass　fraction　of　ore　with　grain　size　of　less　than　0.074　mm)　is　less　than　60%.　The　designed　Graphical　User　Interface　can　be　very　convenient　and　precise　for　calculating　the　Bond　work　index　of　ball　mill　of　Bangpu　Mo-Cu　ore　Crushed　by　HPGR　and　any　grinding　fineness　the　Bond　work　index　of　ball　mill　requires.