Two　unique　heterometallic　cluster　organic　frameworks,　[Cd4MnIII4MnII6(Tri)4(CH3COO)14(μ4-O)2(μ3-O)2(H2O)2]　Cd(H2O)2⋅9　H2O　(1)　and　Cu[Cd5Cu6(Tri)4(CH3COO)9(H2O)4]2(CH3COO)3⋅24　H2O　(2)　(H3Tri=2-(hydroxymethyl)-2-(pyridine-4-yl)-1,3-propanediol),　have　been　successfully　prepared　by　employing　a　bifunctional　tripodal　alcohol　ligand　as　a　structure-directing　agent.　Crystal　structure　analyses　reveal　that　1　represents　a　rare　example　of　frameworks　constructed　from　Cd−Mn　heterometallic　chains,　and　2　is　the　first　heterometallic　MOF　based　on　highest-nuclear　Cd−Cu　heterometallic　cluster　building　blocks.　Furthermore,　the　magnetic　properties　and　gas　adsorption　abilities　of　1　and　2　were　systematically　studied.　©　2019　Wiley-VCH　Verlag　GmbH　&　Co.　KGaA,　Weinheim