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A method based on reversed-phase liquid chromatography-tandem mass spectrometry (LC/MS/MS) combined with solid phase extraction (SPE) was developed and validated for qualitative and quantitative detection of eight parabens in three types of water-based food simulants including distilled water, 3% acetic acid, 10% alcohol. Detection limits of eight parabens after SPE procedure were 0.005-0.010 mu g/L in distilled water, 0.006-0.015 mu g/L in 3% acetic acid and 0.005-0.017 mu g/L in 10% alcohol. The relative standard deviations (RSDs) were in the range of 1.90-8.48% for distilled wsater, 1.01-3.73% for 3% acetic acid and 5.78-12.97% for 10% alcohol. The method could make a complement for detecting parabens migrated to food and feeds.
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MEASUREMENT TECHNOLOGY AND ENGINEERING RESEARCHES IN INDUSTRY, PTS 1-3
ISSN: 1660-9336
Year: 2013
Volume: 333-335
Page: 1993-,
Language: English
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ESI Highly Cited Papers on the List: 0 Unfold All
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30 Days PV: 2
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