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Abstract:
Binding of Pt-drugs to DNA significantly enhaces base damages, crosslinks, double strand breaks (DSBs) and non-DSB cluster lesions induced by 10 eV electrons. This enhancement of potentially lethal lesions is due to a modification of electron-DNA interactions, which contributes to the synergy between chemo- and radio-therapy, when these modalities are administered in concomitance during cancer treatments.
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31ST INTERNATIONAL CONFERENCE ON PHOTONIC, ELECTRONIC AND ATOMIC COLLISIONS (ICPEAC XXXI)
ISSN: 1742-6588
Year: 2020
Volume: 1412
Language: English
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SCOPUS Cited Count:
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
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30 Days PV: 0
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