It　was　found　that　meloxicam　could　enhance　the　chemiluminescence　(CL)　of　the　tris(2,2＇-bipyridine)　ruthenium(II)Ce(IV)　system　in　the　medium　of　sulfate　acid.　Based　on　this　phenomenon　a　new　flow-injection　system　with　chemiluminescent　detection　has　been　proposed　for　determination　of　meloxicam.　Under　optimum　conditions,　meloxicam　had　a　good　linear　relationship　with　the　CL　intensity　in　the　concentration　range　of　6.0　x　10(-4)　to　1.0　mu　g/mL　and　the　detection　limit　was　3.7　x　10(-4)　mu　g/mL.　The　proposed　method　was　applied　to　detect　meloxicam　in　tablets　and　a　satisfactory　recovery　was　obtained.　The　possible　mechanism　for　this　CL　system　is　also　discussed　in　this　paper.　Copyright　(C)　2009　John　Wiley　&　Sons,　Ltd.