Arsenic bioavailability and transformation from As(V)-sorbed aluminum oxides: The influence of Fe(III) and human gut microbiota - Details

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Abstract：

Minerals　control　on　the　oral　bioavailability　of　arsenic　(As)　in　soil　has　been　evidenced　in　human　health　risk　assessments.　However,　little　is　known　about　the　metabolism　of　soil　mineral-associated　As　by　human　gut　microbiota.　This　study　evaluated　the　relative　bioavailability　(RBA)　and　bioaccessibility　of　As　in　As(V)-sorbed　Aluminum　(Al)　oxides　(α-Al2O3　and　γ-Al2O3),　affected　by　gut　microbiota　and　Fe(III).　The　in　vitro　method　yielded　higher　As　bioaccessibility　in　the　small　intestinal　phase　of　α-Al2O3　(30.3　%–54.8　%)　and　in　the　colon　phase　of　γ-Al2O3　(29.7　%–45.6　%),　respectively.　In　the　presence　of　Fe,　As　release　was　decreased　by14.5　%–48.1　%　in　the　small　intestine　but　increased　by　37.5　%–86.3　%　in　the　colon　(p　©　2025　Elsevier　B.V.

Keyword：

Alkylation Aluminum oxide Bioassay Biochemistry Health risks Iron compounds Risk assessment

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[ 1 ] [Xiao, Peng]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China
[ 2 ] [Li, Yan]Chinese Research Academy of Environmental Sciences, Beijing; 100012, China
[ 3 ] [Xiong, Shimao]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China
[ 4 ] [Zhou, Yi]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China
[ 5 ] [Yin, Naiyi]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China
[ 6 ] [Li, Yunpeng]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China
[ 7 ] [Jiang, Xiyan]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China
[ 8 ] [Chang, Xuhui]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China
[ 9 ] [Wang, Pengfei]Yunnan Provincial Key Lab of Soil Carbon Sequestration and Pollution Control, Faculty of Environmental Science & Engineering, Kunming University of Science & Technology, Yunnan, Kunming; 650500, China
[ 10 ] [Cai, Xiaolin]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China
[ 11 ] [Chen, Xiaochen]Innovation Center for Soil Remediation and Restoration Technologies, College of Environment and Safety Engineering, Fuzhou University, Fuzhou; 350108, China
[ 12 ] [Guo, Guanlin]Technical Centre for Soil, Agricultural and Rural Ecology and Environment, Ministry of Ecology and Environment, Beijing; 100012, China
[ 13 ] [Cui, Yanshan]College of Resources and Environment, University of Chinese Academy of Sciences, Beijing; 101408, China

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Source ：

Journal of Hazardous Materials

ISSN： 0304-3894

Year： 2025

Volume： 496

1 2 . 2 0 0

JCR@2023

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ESI Highly Cited Papers on the List： 0 Unfold All

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