Tin-oxo　clusters,　characterized　by　their　well-defined　chemical　compositions　and　architectures,　are　multi-metal　aggregates　composed　of　Sn-oxide　cores　and　surface　ligands.　Chirality,　a　fundamental　characteristic　governing　biological　recognition　and　signal　transduction,　remains　underexplored　in　stannate　clusters　compared　to　extensively　studied　precious　metal　clusters.　Herein,　three　enantiomeric　pairs　of　chiral　tin-oxo　clusters　were　constructed　using　axially　chiral　1,1　＇-bi-2-naphthol　(BINOL)　ligands.　Structural　analyses　revealed　supramolecular　helical　assemblies　mediated　by　directional　C　&　horbar;Hpi　interactions,　while　circular　dichroism　(CD)　spectroscopy　confirmed　their　intrinsic　chirality.　Through　in　situ　doping　engineering,　non-chiral　fluorophores　with　distinct　emission　profiles　were　incorporated　during　chiral　cluster　crystallization,　yielding　composite　materials　exhibiting　circularly　polarized　luminescence　(CPL).　The　optimized　system　achieved　a　maximum　dissymmetry　factor　(glum)　of　1.5　x　10-2.　Mechanistic　studies　established　that　the　spiral　packing　of　the　tin-oxo　clusters　facilitates　stereochemical　information　transfer　to　the　dyes　via　the　spatial　confinement　effect.　This　supramolecular　chirality　induction　paradigm　offers　new　insights　into　the　rational　design　of　multifunctional　optical　materials.