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author：

Wu, W.-R. (Wu, W.-R..) [1] | Li, J. (Li, J..) [2] | Lin, Y. (Lin, Y..) [3] | Luo, F. (Luo, F..) [4] (Scholars：罗芳) | Lin, C.-Y. (Lin, C.-Y..) [5] (Scholars：林翠英) | Qiu, B. (Qiu, B..) [6] (Scholars：邱彬) | Lin, Z.-Y. (Lin, Z.-Y..) [7] (Scholars：林振宇) | Wang, J. (Wang, J..) [8] (Scholars：王建) | Huang, F.-Z. (Huang, F.-Z..) [9]

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Scopus SCIE

Abstract：

This　study　presents　a　smartphone-integrated　portable　platform　for　rapid　lactic　acid　(LA)　analysis　using　ratiometric　fluorescent　imaging.　The　system　employs　a　dual-emission　probe　composed　of　glutathione-modified　gold　nanoclusters　(GSH-AuNCs)　and　carbon　quantum　dots　(CDs),　enabling　visual　detection　via　fluorescence　color　transitions　under　365　nm　UV　excitation.　As　LA　concentration　increases,　the　fluorescence　shifts　from　blue　to　orange.　Smartphone　photography　and　RGB　color　analysis　reveal　a　nonlinear　sigmoidal　correlation　between　the　red-to-blue　intensity　ratio　(R/B)　and　LA　concentration,　modeled　with　a　coefficient　of　determination　(R2　=　0.998).　The　method　exhibits　high　selectivity　and　achieves　recovery　rates　of　94.5–104.8　%　in　sweat　samples,　validated　against　LC-MS.　This　technology　offers　a　novel,　on-site　solution　for　food　quality　assessment　and　health　monitoring　applications.　©　2025　Elsevier　B.V.

Keyword：

Lactic acid Ratiometric fluorescence sensing Smartphone colorimetry

Community：

  • [ 1 ] [Wu W.-R.]Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 2 ] [Li J.]Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 3 ] [Lin Y.]Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 4 ] [Luo F.]College of Biological Science and Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 5 ] [Lin C.-Y.]Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 6 ] [Qiu B.]Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 7 ] [Lin Z.-Y.]Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 8 ] [Wang J.]Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 9 ] [Huang F.-Z.]Department of Traditional Chinese Medicine, Fuzhou First General Hospital Affiliated with Fujian Medical University, Fujian, Fuzhou, 350009, China

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Source ：

Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

ISSN： 1386-1425

Year： 2025

Volume： 338

4 . 3 0 0

JCR@2023

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ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 6

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生物科学与工程学院 本学院/部未明确归属的数据

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