As　industrial　development　advances，　the　intensification　of　heavy　metal　and　radioactive　substance　pollution　has　coincided　with　a　growing　demand　for　rare　metals.　Consequently，it　is　essen⁃　tial　to　implement　a　process　of　separation　and　enrichment　of　metals.　Covalent　organic　frameworks　（COFs），which　are　distinguished　by　large　specific　surface　area，high　porosity，high　crystallinity，　and　adjustable　pore　size，have　emerged　as　promising　materials　for　metal　separation　and　enrichment.　The　selectivity　of　COFs　for　specific　metal　ions　can　be　enhanced　through　the　incorporation　of　tailored　functional　groups.　Furthermore，the　robust　covalent　bonds　within　COFs　contributes　to　their　stability　in　harsh　environments.　Given　the　above，this　paper　offers　a　comprehensive　overview　of　the　applica⁃　tion　of　COFs　in　metal　separation　and　enrichment　in　recent　years.　It　focuses　on　the　diverse　connection　modes　of　COFs　and　their　associated　separation，enrichment，and　adsorption　mechanisms　in　precious　metals，heavy　metals，rare　earth　elements，and　radioactive　elements.　Finally，the　article　address⁃　es　presents　a　comprehensive　analysis　of　the　challenges　associated　with　the　practical　application　of　COFs　for　the　separation　and　enrichment　of　metals，while　also　offering　insights　for　future　research.　©　2025,　China　Association　for　Instrumental　Analysis.　All　rights　reserved.