ContextLandscape　metrics　can　effectively　quantify　urban　landscape　dynamics　and　their　ecological　stress,　but　incorrect　metric,　scale　and　zoning　choices　may　lead　to　inaccurate　result　and　biased　land　use　planning.ObjectivesThis　study　aims　to　explore　how　the　scale　and　zoning　affected　the　magnitude　and　spatial　pattern　of　ecological　stress　delineated　by　two　related　landscape　metrics-　Eco-erosion　index(EEI)　and　percent　of　built-up　area　(PB).MethodsWe　quantified　ecological　stress　from　urban　expansion　using　EEI　and　PB　across　different　scales　and　zoning　patterns,　based　on　30　m　land　use　and　land　cover　(LULC)　data　of　Shanghai,　China.　Descriptive　and　non-parametric　statistics　were　used　to　analyze　the　sensitivity　and　spatial　heterogeneity　of　EEI　and　PB　in　response　to　variations　in　grain　size,　extent,　and　zoning.ResultsOur　findings　indicate　that　EEI　and　PB　are　more　sensitive　to　changes　in　extent　than　in　grain　size.　EEI　is　better　at　capturing　spatial　heterogeneity　of　ecological　stress　in　detail　compared　to　PB　at　the　same　zoning　pattern.　Statistically,　zoning　patterns　don＇t　affect　the　ranking　of　ecological　stress　levels　among　study　units.　However,　EEI　using　fine-scale　zoning　is　more　appropriate　for　highlighting　discrepancies　within　the　city　than　using　broad-scale　zoning　at　the　same　grain　size.　It　is　also　recommended　that　the　minimum　study　unit　for　EEI　estimated　with　30　m　LULC　grain　size　should　be　no　smaller　than　a　5　km　by　5　km　grid　cell.ConclusionsThis　study　emphasizes　scale　and　zoning　effects　on　EEI　and　PB,　providing　guidance　for　using　these　metrics　to　represent　ecological　stress　and　contributing　to　sustainable　urban　planning.