Iron-modified　Ni(OH)2/NiSe2　enhances　oxygen　vacancies,　expanding　the　electrochemically　active　surface　area,　which　exhibiting　superior　selectivity　and　stability　in　urea　oxidation　reaction,　outperforming　pristine　Ni(OH)2@NiSe2.　It　also　demonstrates　superior　catalytic　performance　in　the　oxidation　reactions　of　other　small　molecules.　The　moss-like　Fe-Ni(OH)2@NiSe2　catalyst　shows　good　catalytic　ability　for　nucleophiles　(e.g.,　ammonia,　methanol　and　urea).　Notably,　the　electrocatalytic　activity　for　the　urea　oxidation　reaction　is　the　best,　and　it　shows　good　electrochemical　stability.