Copper-based　small-pore　zeolites　catalysts　are　the　promising　candidate　catalysts　for　NOx　abatement　in　current　diesel　vehicles　with　Chinese　VI　standards,　due　to　the　excellent　NH3-SCR　catalytic　performance,　hydrothermal　stability,　nitrogen　selectivity　and　wide　temperature　window.　However,　the　catalytic　activity　of　copper-based　small-pore　zeolites　is　still　significantly　affected　by　sulfur　oxides　emitted　from　diesel　vehicles,　and　even　the　irreversible　deactivation　occurs.　The　SO2-poisoning　of　Cu-based　small-zeolites　is　mainly　due　to　the　accumulation　of　surface　ammonium　sulfate　and　sulfation　of　Cu　active　site　sites.　In　this　review,　the　research　status　of　the　structure　and　active　sites　of　copper-based　small-pore　zeolites　catalysts　is　summarized,　and　the　sulfur　poisoning　mechanism　of　copper-based　small-pore　zeolites　catalysts　is　discussed.　Moreover,　the　research　advance　in　the　improvement　of　sulfur　resistance　of　catalysts　and　the　regeneration　of　sulfur-poisoned　catalysts　is　also　illustrated.　The　systematic　understanding　of　mechanism　of　sulfur　poisoning　and　regeneration　is　important　for　the　design　of　novel,　efficient　catalyst.　It　is　pointed　out　that　the　study　on　sulfur　poisoning　mechanism　and　regeneration　mechanism　of　copper-based　small-pore　zeolites　catalysts,　as　well　as　the　synergistic　effect　of　various　poisoning　factors　and　corresponding　deactivation　mechanism,　are　the　main　research　directions　for　copper-based　zeolites　to　be　practically　applied　to　ultra-low　emission　of　nitrogen　oxides　in　diesel　vehicle　exhaust　in　the　future.