The　adoption　of　protection　routing　guarantees　the　existence　of　a　loop-free　alternate　path　for　packet　forwarding　when　a　single　link　or　node　failure　occurs.　By　Tapolcai＇s　method,　the　presence　of　two　completely　independent　spanning　trees　(CISTs　for　short)　suffices　to　configure　a　protection　routing.　This　article　extends　the　idea　of　protection　routing　to　involve　more　CISTs　and　attach　a　secure　mechanism　in　the　configuration,　which　we　call　the　secure　multi-protection　routing　scheme　(SMPR-scheme).　Then,　we　use　the　SMPR-scheme　to　deal　with　privacy-preserving　data　transmissions,　such　as　downloading　personal　medical　records,　tax　bills,　or　other　private　information.　To　evaluate　the　effectiveness　of　the　SMPR-scheme,　we　develop　a　probabilistic　model　that　allows　some　malicious　nodes　to　collect　information　illegally　through　neighboring　access.　We　experimented　with　SMPR-scheme　on　the　BCube　(i.e.,　the　generalized　hypercube)　datacenter　network.　Simulation　results　show　that　data　transmission　using　SMPR-scheme　ensures　confidentiality　(i.e.,　no　node　other　than　the　recipient　can　receive　the　complete　message)　and　effectively　resists　privacy　collection　even　under　malicious　infringement.　(C)　2022　Elsevier　Inc.　All　rights　reserved.