Silver　nanoparticles　(AgNPs)　are　widely　adopted　in　polyurethane　foams　(PUFs)　as　a　type　of　antibac-terial　agent.　However,　due　to　its　poor　interfacial　interaction,　AgNPs　are　difficult　to　be　dispersed　in　the　polymer　matrix　uniformly,　which　deteriorates　the　enhancement　effect.　In　this　paper,　silver-coated　graphene　nanocomposite　(Ag/GO)　is　prepared　by　an　enzyme　reductant　which　is　efficient　and　non-toxic.　Compared　with　traditional　antibacterial　agent,　the　Ag/GO　nanoparticles　can　be　uniformly　dispersed　in　the　nanocomposite,　which　means　that　Ag/GO　can　be　well-dispersed　into　the　polyurethane　foams　(PUFs).　Compared　with　AgNPs　modified　PUFs,　the　as-prepared　Ag/GO　modi-fied　PUFs　have　a　1.85%　improvement　in　resilience,　7.9%　improvement　in　tensile　strength,　6.52%　improvement　in　tensile　elongation,　and　8.74%　improvement　in　bacteriostats　rate　at　a　loading　of　0.4%.