As　a　new　type　of　medical　material,　natural　polymer　hydrogel　can　be　widely　used　in　the　field　of　orthopedics　and　plays　an　important　role　in　bone　tissue　engineering　scaffold　materials.　This　article　mainly　introduces　the　ideal　requirements　of　bone　tissue　engineering　scaffold　materials,　and　elaborates　the　development　status　of　3D　printing　technology　and　biomedical　material　hydrogels.　In　this　paper,　a　new　kind　of　nanocomposite　hydrogel　material　was　prepared　by　combining　GO　and　hyaluronic　acid　with　the　thermal　gelation　property　of　methyl　cellulose　and　modified　polyethylene　glycol　as　crosslinking　agent,　and　its　physical　and　chemical　properties　were　studied.　By　changing　the　concentration　of　graphene　oxide　solution,　in　order　to　obtain　a　better　gel　preparation　program.　©　2021,　The　Author(s),　under　exclusive　license　to　Springer　Nature　Singapore　Pte　Ltd.