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Abstract:
We reported herein a visible light promoted difluoroalkylated cascade of imidazoles and alkenes to afford highly functionalized polycyclic imidazoles. This method features a direct radical cyclization of imidazoles with alkenes using BrCF2R as radical sources. The reaction conditions tolerate a wide range of substrate scope and afford the desired products with up to 95 % isolated yield under mild conditions. Radical-trapping and light-on/off experiments indicated a photocatalytic radical mechanism.
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EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN: 1434-193X
Year: 2021
Issue: 31
Volume: 2021
Page: 4485-4489
3 . 2 6 1
JCR@2021
2 . 5 0 0
JCR@2023
ESI Discipline: CHEMISTRY;
ESI HC Threshold:117
JCR Journal Grade:2
CAS Journal Grade:3
Cited Count:
WoS CC Cited Count: 12
SCOPUS Cited Count: 12
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 2
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