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Abstract:
We disclose herein a photocatalytic difluoroalkylation and cyclization cascade reaction of N-(but-2-enoyl)indoles with broad substrate scopes in up to 90% isolated yield. This method provides sustainable and efficient access to synthesize difluoroalkylated pyrrolo[1,2-a]indoles with a quaternary carbon center under mild conditions.
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JOURNAL OF ORGANIC CHEMISTRY
ISSN: 0022-3263
Year: 2018
Issue: 4
Volume: 83
Page: 2425-2437
4 . 7 4 5
JCR@2018
3 . 4 0 0
JCR@2023
ESI Discipline: CHEMISTRY;
ESI HC Threshold:209
JCR Journal Grade:1
CAS Journal Grade:2
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