Indexed by:
Abstract:
本研究将质粒pYG836转化到柔红霉素产生菌SIPI—DM中,采用同源重组双交换法,用aveBIV因置换基因组上的dnmV基因,得到稳定遗传的表柔红霉素工程菌DM3。为进一步提高工程菌的发酵单位,对其原生质体进行连续4次的紫外诱变育种,最终得到一株发酵单位较出发菌株提高了93.7%的突变菌株。
Keyword:
Reprint 's Address:
Email:
Source :
中国医药工业杂志
ISSN: 1001-8255
Year: 2009
Issue: 1
Volume: 40
Page: 20-23
Cited Count:
WoS CC Cited Count: 0
SCOPUS Cited Count:
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count: -1
30 Days PV: 1
Affiliated Colleges: