To　investigate　typoglycemic　activity　with　triterpene　acid　extracted　from　loquat　leaf.　Using　gliclazide　and　metformin　hydrochloride　as　the　positive　control,　the　influences　of　loquat　leaf　triterpenic　acids　extracts　(LTAE)　on　fasting　blood　glucose　levels　of　normal　mice　were　investigated;　the　influences　of　LTAE　on　glucose　and　starch　tolerance　of　normal　taken　orally　and　the　influences　ofLTAE　on　blood　glucose　levels　of　diabetic　mice　were　all　investigated.　Compared　with　gliclazide　(100　mg/kg,　P　＜0.01),　crude　triterpenic　acids　from　loquat　leaf　(CTAL)　and　corosolic　acid　from　loquat　leaf　(CAL)　have　no　effect　on　fasting　blood　glucose　levels　of　normal　mice;CTAL(400　mg/kg)　can　inhibit　obviously　the　blood　glucose　rising　after　administrating　glucose　to　fasting　normal　mice　by　i.　g.,　it　has　equal　effect　with　metformin　hydrochloride.　However,　for　CAL,　this　inhibiting　effect　is　not　obviousl;　CTAL　(400　mg/kg)　can　inhibit　significantly　the　blood　glucose　rising　after　administrating　starch　to　fasting　normal　mice　by　i.　g.,　even　stronger　than　metformin　hydrochloride.　CAL　can　inhibit　this　obviously　too;　Compared　with　gliclazide　(100mg/kg,　P　＜0.01),　CTAL　and　CAL　show　no　effect　on　blood　glucose　levels　of　diabetic　mice.　Loquat　leaf　extracts　have　a　good　control　activity　of　postprandial　blood　glucose　while　they　dont　affect　the　normal　glucose　level.　So　we　can　say　that　these　extracts　have　a　good　prospect　of　being　developed　into　weight　-　loss　products　or　related　drugs.