A　new　method　for　analyzing　diuretics　by　capillary　electrochromatography　using　poly　(1-hexadecene-co-TMPTMA)　monolithic　column　was　established.　Experimental　conditions　including　the　mobile　phase,　separation　voltage,　and　injection　condition　were　optimized　for　the　analysis.　Under　optimized　experimental　conditions,　six　diuretics　were　separated　within　11.0　min　with　the　limits　of　detection　(LODs)　(S/N　=3)　in　the　range　of　0.　35　-　0.　65　μ/mL.　The　method　showed　good　linearity　(R2≥0.　990　8)　in　the　range　1.　15　and　86.　0　μ/mL.　The　recoveries　obtained　from　the　analysis　of　spiked　urine　sample　were　between　81.　9%　and　105%　with　the　relative　standard　deviations　(RSDs)　lower　than　4.　7%.　It　can　be　concluded　that　this　new　method　possessed　good　repeatability　and　stability　in　analyzing　diuretics,　and　was　successfully　applied　to　the　analysis　of　real　urine　samples　from　volunteers.　Therefore,　this　method　could　be　applied　to　scanning　dituretics　in　human　urine　samples.