Uranium　in　the　environment　can　damage　human　health　and　ecosystem.　There　is　a　need　for　excellent　adsorbents　to　remove　U(VI)　from　aqueous　solutions.　Here　we　synthesized　a　novel　β-cyclodextrin/poly(acrylic　acid)/permutite　(CAP)　hydrogel　composite　by　a　simple　method.　Physicochemical　characterizations　of　the　materials　were　conducted　by　XRD,　FTIR,　SEM,　EDX,　and　TGA.　The　effect　of　pH　value,　contact　time,　initial　U(VI)　concentration,　and　temperature　were　researched.　A　pseudo-second-order　kinetic　model,　intra-particle　diffusion　model,　and　Langmuir　isotherm　model　were　used　to　describe　the　U(VI)　adsorption　behavior,　and　the　maximum　adsorption　capacity　of　U(VI)　was　833.33　mg/g　at　25　℃.　Thermodynamic　analysis　showed　that　the　adsorption　process　of　U(VI)　was　endothermic　and　spontaneous.　Furthermore,　the　excellent　reusability　indicated　that　CAP　hydrogel　composite　could　be　potentially　used　as　a　promising　sorbent　for　the　removal　of　U　(VI)　in　wastewater.　©　2020　Fujian　Institute　of　Research　of　the　Structure　of　Matter.　All　rights　reserved.