The　recent　progress　was　presented　briefly　on　the　characterization　method　of　the　isomers　of　tetra-substituted　metal　phthalocyanines　by　1H　NMR.　The　tetra-substituted　metal　phthalocyanines　were　constituted　by　four　isomers　and　eight　magnetically　nonequivalent　isoindole　units,　which　exert　an　influence　on　the　protons　of　both　the　aromatic　ring　and　substituted　groups.　Therefore,　the　symmetry　of　isomers　can　be　confirmed　by　analysis　of　the　1H　NMR　spectra　of　these　protons.