This　paper　mainly　describes　the　sensor　data　acquisition　interface　system　that　is　implemented　by　open　source　Microcontroller　Unit　(MCU)　soft　core　transplantation　based　on　FPGA　and　cooperating　with　the　FPGA　to　implement　the　calculation　module　to　achieve　peripheral　sensor　management,　data　acquisition　and　interaction,　which　isabletobeused　for　Internet　of　Things　(IoT)　sensor　data　acquisition.　After　the　sensor　collects　the　data,　the　preliminary　data　processing　operation　is　completed　by　the　calculation　module　instantiated　by　the　FPGA,　and　then　the　result　is　returned　to　the　MCU　to　realize　the　local　storage　of　the　final　data　and　the　Ethernet　transmission.　The　system　is　designed　on　the　basis　of　a　Heterogeneous　System　Architecture　(HSA)　which　is　based　on　an　open　source　soft　core　supplemented　by　a　FPGA.　This　method　achieves　acceleration　of　data　processing,　with　strong　flexibility　and　high　portability.　It　can　replace　various　sensors　for　data　interaction　of　the　Internet　of　Things　system.　©　2018　IEEE.