The　D-glucoseamine　was　grafted　to　ultrahigh　molecular　weight　poly(styrene-alt-maleic　anhydride)　via　graft-to　copolymerization　method　in　solution.　The　structure　and　molecular　weight　of　the　resultant　amphiphilic　grafted　copolymer　SMA-g-GLA　was　characterized　by　1H　NMR　and　GPC　respectively.　The　SMA-g-GLA　was　blend　with　PVDF　to　fabricate　blend　membranes　by　the　standard　immersion　precipitation　phase　inversion　process.　The　surface　and　cross-section　morphology　of　pure　PVDF　and　blend　PVDF　membranes　were　characterized　by　SEM.　The　surface　hydrophilicity　of　pure　PVDF　and　blend　PVDF　membranes　were　characterized　by　static　water　contact　angle.　The　anti-fouling　property　was　characterized　by　BSA　static　absorb　experiment.