Three　kinds　of　CuFe2O4　catalysts　were　synthesized　by　co-precipitation　method　using　potassium　hydroxide　(A),　sodium　carbonate　(B)　and　sodium　bicarbonate　(C)　as　the　precipitants.　Their　catalytic　activity　and　thermal　stability　were　evaluated　in　water-gas　shift　reaction　(WGSR).　The　microstructure　and　surface　property　of　as-prepared　catalysts　was　investigated　by　X-ray　diffraction　(XRD),　N2-physisorption,　H2-temperature　programmed　reduction　(H2-TPR),　CO2-temperature　programmed　desorption　(CO2-TPD)　and　cyclic　voltammetry　(CV).　The　results　show　that　the　catalyst　prepared　with　potassium　hydroxide　as　precipitant　exhibits　excellent　WGSR　activity.　Potassium　hydroxide　plays　an　important　role　in　promoting　the　generation　of　CuFe2O4,　restraining　growth　of　crystalline　CuO　and　CuFe2O4,　resulting　in　much　better　dispersion　of　CuO　on　the　surface　of　catalysts,　enhancing　the　reducibility　of　catalysts,　and　increasing　the　amount　of　weak　basic　sites.　These　factors　remarkably　improve　the　activity　and　thermal　stability　of　catalysts.