Magmatic　activities　were　very　active　in　the　middle　section　of　the　Gangdise　during　Mesozoic　to　Cenozoic　periods,　but　petrogenesis　and　magma　source　of　this　area　is　still　in　dispute.　The　Early　Cretaceous　magmatism　is　not　only　key　element　for　understanding　magmatism-related　mineralization　temporally　concentrated　in　the　Gangdise,　but　also　a　window　for　probing　geodynamic　process.　With　the　Early　Cretaceous　granite　complex　in　the　Quejiaonong　area　as　an　example,　we　conducted　an　integrated　study　of　petrology,　zircon　U-Pb　age,　and　elemental　geochemistry　and　Sr-Nd　isotopes.　Lithological　assemblages　of　granitoid　rock　are　dominated　by　biotite　granodiorite　with　minor　quartz　monzonite　and　rare　K-feldspar　granite,　and　belong　to　high-K　calc-alkaline　and　I　type　granitoids.　Zircon　U-Pb　dating　indicates　that　the　biotite　granodiorite　rocks　were　emplaced　at　127±1.6Ma　and　are　characterized　by　high　(87Sr/86Sri)　ratio　(0.70926-0.71424),　negative　whole-rock　ΕNd(t)　value　(-7.0~-9.1),　enrichment　in　large　ion　lithophile　elements　and　depletion　in　high　field　strength　elements,　displaying　an　affinity　of　volcanic　arc　granite.　The　magma　was　sourced　from　antexis　of　ancient　lower　crust　materials　and　minor　mixed　mantle-derived　melts,　experienced　significant　fractional　crystallization.　Lithogenesis　of　the　pluton　was　likely　related　to　the　slab　break-off　during　southward　subduction　of　Bangong-Nujiang　Tethys　oceanic　crust　during　the　Early　Cretaceous.　The　Quejiaonong　pluton　was　a　continuation　of　eruption　event　of　strip　magma　in　the　middle　Gangdese　in　Early　Cretaceous,　resulting　in　strong　alteration　between　the　pluton　and　country　rocks.　High　geophycial　anomalous　values　indicate　iron　and　tungsten　mineralization　with　locally　mineralized　prospects　of　magnetite.　Ore-forming　plutons　have　high　Ce4+/Ce3+　ratios　(450-769)　and　temperature　calculated　by　Ti-in-zircon　thermometeris　was　ca.　776,　indicating　that　the　ore-bearing　magma　was　characterized　by　a　relatively　high　oxygen　fugacity　and　high　diagenetic　temperature.　Spatial　distribution　of　geochemical　trend　residual　anomalies　is　controlled　by　geochemical　anomalies　is　controlled　by　strata,　fault　structure　and　magmatic　rocks,　suggesting　a　promising　outlook　for　iron　and　tungsten　exploration　in　this　area.　©　2017,　Science　Press.　All　right　reserved.