This　article　aimed　at　studying　the　separation　of　water　phase　by-products　produced　by　slurry　bed　process　with　cobalt-based　catalyst　in　Fischer-Tropsch　synthesis.　A　separation　project　about　pervaporation　and　distillation　was　put　forward　to　instead　of　the　multi-columns　distillation　technology　which　was　high　energy　consumption　to　separate　alcohol　and　water.　The　new　technology　remained　dehydrating　tower　and　crude　distillation　tower　in　multi-columns　distillation　technology,　while　C1-C3　alcohol-water　mixture　was　dehydrated　by　pervaporation　technology,　replacing　the　traditional　distillation　technology.　The　results　showed　that　NaA　zeolite　molecular　sieve　permeable　membrane　was　a　suitable　material　for　separation,　and　the　permeation　flux　can　reach　2.4　kg/(m2·h).　The　water　content　of　water　phase　by-products　in　Fischer-Tropsch　synthesis　was　reduced　from　17.09%　to　below　0.5%　by　pervaporation-distillation　process.　In　addition,　the　energy　consumption　between　pervaporation-distillation　process　and　multi-columns　distillation　process　was　compared.　It　was　found　that　the　energy　consumption　of　pervaporation　and　distillation　coupling　process　can　save　approximately　24%.　©　2017,　Chemical　Industry　Press.　All　right　reserved.