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author:

Tang, Yun-dong (Tang, Yun-dong.) [1] | Flesch, Rodolfo C.C. (Flesch, Rodolfo C.C..) [2] | Zhang, Cheng (Zhang, Cheng.) [3] | Jin, Tao (Jin, Tao.) [4]

Indexed by:

EI

Abstract:

Magnetic hyperthermia ablates malignant cells by the heat produced by power dissipation of magnetic nanoparticles (MNPs) under an alternating magnetic field. Most of the works in literature consider a uniform magnetic field for solving numerical models to estimate the temperature field during a hyperthermia treatment, however this assumption is generally not true in real circumstances. This paper considers the magnetic field produced by a solenoid and analyzes its effects on the treatment temperature. To that end, a set of partial differential equations is numerically solved for a specific tumor model using the finite element method and the obtained results are analyzed to draw general conclusions. The magnetic field inside the solenoid is obtained by using Maxwell's theory, and the treatment temperature of the tumor model is determined by using Rosensweig's theory and Pennes bio-heat transfer equation. Simulation results demonstrate that the temperature field obtained using a solenoid model is similar to that obtained considering a uniform magnetic field if tumor is centered with respect to solenoid and if the physical characteristics of solenoid are properly defined based on tumor volume. As the distance of tumor from the solenoid center is increased, the effects of non-uniformity of magnetic field become more evident and the adoption of the proposed model is necessary to obtain accurate results. © 2017 Elsevier B.V.

Keyword:

Heat transfer Hyperthermia therapy Magnetic field effects Magnetic fields Maxwell equations Nanomagnetics Nanoparticles Solenoids Temperature Temperature distribution Tumors

Community:

  • [ 1 ] [Tang, Yun-dong]College of Physics and Information Engineering, Fuzhou University, Fuzhou; 350116, China
  • [ 2 ] [Flesch, Rodolfo C.C.]Departamento de Automação e Sistemas, Universidade Federal de Santa Catarina, Florianópolis; SC; 88040-900, Brazil
  • [ 3 ] [Zhang, Cheng]School of Information Science and Engineering, Fujian University of Technology, Fuzhou; 350118, China
  • [ 4 ] [Jin, Tao]College of Electrical Engineering and Automation, Fuzhou University, Fuzhou; 350116, China

Reprint 's Address:

  • [jin, tao]college of electrical engineering and automation, fuzhou university, fuzhou; 350116, china

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Source :

Journal of Magnetism and Magnetic Materials

ISSN: 0304-8853

Year: 2018

Volume: 449

Page: 455-460

2 . 6 8 3

JCR@2018

2 . 5 0 0

JCR@2023

ESI HC Threshold:158

JCR Journal Grade:2

CAS Journal Grade:3

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 3

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