Fluorescence　resonance　energy　transfer　(FRET)　is　the　radiation　process　which　the　donor　molecules　at　the　excited　state　transferred　capacity　to　the　acceptor　molecules　via　remote　dipole.　Aptamers　can　specially　recognize　its　target　molecules.　Based　on　these　principles,　a　sensitive　and　selective　fluorescent　sensor　for　bisphenol　A　(BPA)　has　been　designed.　The　fluorescence　intensity　of　the　sensing　system　increased　gradually　with　the　increasing　of　BPA　concentration.　Delta　F　has　a　linear　relationship　with　the　logarithm　of　BPA　concentration　in　the　range　of　0.1　nM　-　10　nM　concentration　with　a　correlation　coefficient　(R)　of　0.9986　and　the　detection　limit　of　0.07　nM　(defined　as　S/N=3).　The　proposed　fluorescent　sensor　has　good　selectivity　for　BPA　assay　even　in　the　presence　of　higher　concentration　of　interferents.