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The electrochemical behavior of two new synthesized biacridine derivatives, 3, 3' -disulfonyl-9,9'-biacridine dinitrate (DSBADN) and 10,10'-dimethyl-3,3'-disulfonyl-9,9'-biacridine (DMDSBA) was investigated by means of cyclic voltammetry and linear sweep polarography. In a HCl solution, the reduction peak current was proportional to the concentrations of DSBADN and DMDSBA. The electrochemical study demonstrated that the reduction peak currents of DSBADN and DMDSBA exhibited adsorptive and diffusion-controlled characteristics, and the electrode reaction was totally irreversible. Tryptophan(Trp) and Histidine(His) could inhibit the reduction peak currents of DSBADN and DMDSBA respectively, the extent of the inhibition was proportional to the concentrations of Trp and His. Based on this principle, a new electrochemical system has been developed for determination of Trp and His.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
ISSN: 1005-9040
CN: 22-1183/O6
Year: 2001
Issue: 4
Volume: 17
Page: 394-399
0 . 2 2 3
JCR@2001
3 . 1 0 0
JCR@2023
ESI Discipline: CHEMISTRY;
JCR Journal Grade:4
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ESI Highly Cited Papers on the List: 0 Unfold All
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Chinese Cited Count:
30 Days PV: 1
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