In　this　paper,　it　was　found　that　Ru(H(2)bpp)(2)(PF6)(2)　(H(2)bpp　=　2,6-bis(pyrazol-3-yl)pyridine)　complex　had　excellent　electrochemical　activity　at　the　carbon　paste　electrode　in　the　buffer　solution　of　Tris-HCl　(pH　7.0)　with　a　couple　reversible　redox　peaks　at　0.296　V　and　0.348　V,　respectively.　Voltammetry　was　used　to　investigate　the　electrochemical　behavior　of　Ru(H(2)bpp)(2)(PF6)(2)　and　the　interaction　between　Ru(H(2)bpp)(2)(PF6)(2)　and　bovine　serum　albumin　(BSA).　In　the　present　of　BSA,　the　oxidation　peak　current　of　Ru(H(2)bpp)(2)(PF6)(2)　complex　was　decreased　linearly　and　the　decrease　of　oxidation　peak　current　of　Ru(H(2)bpp)(2)(PF6)(2)　is　proportional　to　BSA　concentration　from　0.1　to　2.5　mg/L　with　a　detection　limit　0.02　mg/L.　(C)　2010　Qiao　Hua　Wei.　Published　by　Elsevier　B.V.　on　behalf　of　Chinese　Chemical　Society.　All　rights　reserved.