A　facile,　effective　method　was　first　used　to　graft　zwitterionic　monomer　sulfobetaine　methacrylate　(SBMA)　onto　the　surface　of　PVDF　membrane　via　physisorbed　free　radical　grafting　technique.　The　mechanism　of　free　radical　initiating　grafting　polymerization　on　PVDF　membrane　was　investigated　preliminarily.　The　key　factors　affecting　the　graft　density　(GD),　include　monomer　concentration,　reaction　time　and　the　temperature,　were　investigated　in　the　present　study.　As　the　result,　the　graft　density　of　PSBMA　on　PVDF　membrane　was　improved　with　the　increasing　of　monomer　concentration　and　reaction　time.　Around　70　degrees　C　was　the　optimum　temperature　for　the　grafting.　Attenuated　total　reflectance/Fourier　transform　infrared　spectroscopy　(FTIR-ATR)　and　X-ray　photoelectron　spectroscopy　(XPS)　were　conducted　to　confirm　the　chemical　composition　of　the　membrane　surface.　The　morphology　of　membranes　was　characterized　by　scanning　electron　microscopy　(SEM).　After　the　PSBMA　was　grafted,　the　hydrophilicity　of　membrane　surface　was　improved.　The　water　contact　angle　decreased　from　59　degrees　to　17　degrees　within　120　s　was　achieved　at　the　surface　of　membrane　with　GD　0.608　mg/cm(2).　The　static　protein　adsorption　and　the　dynamic　fouling-resistance　experiment　demonstrated　that　grafting　PSBMA　on　the　surface　endow　PVDF　membrane　excellent　anti-fouling　ability.　(C)　2012　Elsevier　B.　V.　All　rights　reserved.