In　this　paper,　ovalbumin　(OVA)　stabilized　gold　nanoclusters　(OVA-Au　NCs)　were　used　as　sensing　probes　for　ascorbic　acid　(AA)　detection.　The　fluorescence　of　Au　NCs　was　found　to　be　quenched　effectively　through　the　change　in　the　oxidation　state　of　Au　NCs　by　AA.　Upon　the　addition　of　AA　under　optimal　conditions,　the　fluorescence　intensity　quenched　linearly　with　the　logarithm　of　AA　concentration　over　the　range　of　1.0　nM　to　100　mu　M　with　a　detection　limit　(LOD,　S/N　=　3)　of　0.5　nM.　Results　indicated　that　the　proposed　method　gives　a　good　sensitivity　and　simple　operation　for　detecting　AA.　This　work　also　has　promising　potential　for　protein-modified　Au　NCs.