The　water-gas　shift　reaction　(WGSR)　has　been　carried　out　over　CuO/Fe2O3　catalysts　modified　by　different　loadings　of　Al2O3　(0%-15%　(w)),　prepared　by　a　stepwise　co-precipitation　method.　Composite　mixture　CuFe2O4　was　produced,　and　the　crystalline　size,　redox　property,　and　surface　metallic　Cu　dispersion　were　manipulated.　The　appropriate　introduction　of　Al2O3　can　promote　the　phase　transition　of　spinel　CuFe2O4　from　tetragonal　to　cubic,　inhibit　aggregation　of　Cu-crystallite,　improve　Cu　dispersion,　and　increase　the　amount　of　weak　basic　sites,　as　confirmed　using　powder　X-ray　diffraction　(XRD),　Raman　spectroscopy,　N-2　physisorption,　N2O　decomposition,　and　temperature-programmed　desorption　of　carbon　dioxide　(CO2-TPD)　techniques.　In　addition,　a　temperature-programmed　reduction　of　hydrogen　(H-2-TPR)　technique　was　used　to　investigate　the　reducibility　of　the　modified　CuO/Fe2O3　catalysts.　It　was　found　that　the　Al2O3-doping　plays　an　important　role　in　increasing　the　hydrogen　consumption　of　the　copper　species,　and　decreasing　reduction　temperature.　This　means　that　the　Al2O3　can　promote　a　synergistic　interaction　between　the　copper　and　iron　species　in　the　CuO/Fe2O3　catalysts.　Overall,　the　Al2O3-modified　catalyst　(10%(w))　has　a　smaller　Cu　particle　size,　better　Cu　dispersion,　greater　reducibility,　and　larger　amount　of　weak　basic　sites,　resulting　in　a　much　higher　initial　catalytic　activity　and　better　thermal　stability.