Six　new　compounds,　penicitrinols　L-O　(1-4),　penicillenols　D-1　(9)　and　D-2　(10),　together　with　six　known　compounds　were　isolated　from　the　marine-derived　fungus　Penicillium　citrinum.　Their　structures　were　elucidated　on　the　basis　of　comprehensive　spectral　analysis　and　chemical　methods.　All　the　new　compounds　were　evaluated　for　their　cytotoxic　effects　on　the　A-549,　HL-60　and　SW-620　cell　lines　by　the　MTT　method.　Penicitrinols　L　(1)　and　M　(2)　showed　weak　cytotoxicities　against　SW-620　cell　line,　while　penicillenols　D-1　(9)　and　D-2　(10)　showed　weak　cytotoxicities　against　A-549　and　HL-60　cell　lines,　respectively.