As　a　promising　alternative　clean　energy　to　fossil　fuels,　H-2　has　been　given　increasing　attention,　and　efficient　H-2　production　is　urgently　required.　Photocatalytic　H-2　generation　from　water　splitting　(WS)　is　deemed　to　be　a　promising　and　green　route　for　H-2　production.　TiO2　has　been　widely　utilized　in　WS　owing　to　the　stability,　low　cost,　corrosion　resistance,　and　environmental　safety　properities.　Nevertheless,　two　dominant　defects　(inferior　absorption　performance　in　visible　light　and　recombination　of　photogenerated　e(-)-h(+)　pairs)　still　impede　the　development　of　TiO2.　This　review　offers　a　comprehensive　overview　of　the　progress　of　various　routes　for　TiO2　nanostructures　(0D-3D)　and　diversified　modifications　for　enhanced　H-2　production.　Further,　the　perspectives　and　opportunities　for　TiO2　based　materials　are　promoted.　Persistent　efforts　are　needed　to　equip　the　TiO2　nanomaterials　with　original　advanced　commercialization　and　functionality.